Selank

What is Selank?

Selank is a synthetic heptapeptide analog of the immunomodulatory peptide tuftsin, with the sequence Thr-Lys-Pro-Arg-Pro-Gly-Pro. Originally developed at the Institute of Molecular Genetics of the Russian Academy of Sciences, Selank has been the subject of extensive preclinical and clinical research.

Research Applications

• Anxiolytic Research: Selank has been studied for its effects on anxiety-related behavior in animal models, showing modulation of GABAergic and serotonergic systems without sedative or muscle-relaxant effects.
• Immunomodulatory Activity: As a tuftsin analog, Selank has demonstrated immunomodulatory properties in preclinical studies, influencing the expression of interleukin-6 and other cytokines.
• Cognitive Function: Research suggests Selank may influence memory and learning processes through modulation of BDNF expression in the hippocampus.
• Neuroprotection: Preclinical studies have explored Selank's potential neuroprotective properties, including its effects on oxidative stress markers in neuronal tissue.

Compound Information

• Sequence: Thr-Lys-Pro-Arg-Pro-Gly-Pro
• Molecular Weight: 751.9 Da
• CAS Number: 129954-34-3
• Appearance: White lyophilized powder

Specifications

• Purity: >99% (HPLC verified)
• Form: Lyophilized powder
• Container: Sealed vial (3mL flip-top)
• Storage: -20°C or below, protected from light
• Shelf Life: 2+ years when stored properly
• Certificate of Analysis available on request

Peer-Reviewed References

• Kozlovskii II, et al. "Selank and short peptides of the tuftsin family in the regulation of adaptive behavior in stress." Neurosci Behav Physiol. 2003.
• Zozulya AA, et al. "The inhibitory effect of Selank on enkephalin-degrading enzymes as a possible mechanism of its anxiolytic activity." Bull Exp Biol Med. 2001.
• Ershov FI, et al. "Antiviral activity of immunomodulator Selank in experimental influenza infection." Vopr Virusol. 2009.

For research use only. Not for human consumption. All products are sold strictly for laboratory and research purposes.